NOVA APPLICATIONS
DNASTAR Nova Applications
NovaFold AI & NovaFold AI-Multimer
NovaFold AI & NovaFold AI-Multimer are protein structure prediction applications that enable you to seamlessly utilize the AlphaFold 2 or AlphaFold-Multimer methods to predict the protein structure of an amino acid sequence, and then visualize and analyze your results. AlphaFold 2 was the top-ranked single-chain protein structure prediction method in the CASP14 challenge in 2020, significantly outperforming the other participating teams by determining the structure of proteins with accuracy comparable to laboratory experiments. AlphaFold-Multimer is an extension of the AlphaFold 2 algorithm that has been optimized to predict the structures of multichain protein complexes (multimers). This algorithm was the foundational element of the top three performers in the multimer target class of the CASP15 challenge in 2022. When you access these algorithms through NovaFold AI or NovaFold AI-Multimer, both structure prediction and analysis take place within the existing NovaCloud Services interface of Protean 3D.
NovaFold
NovaFold is protein structure prediction software based on I-TASSER, the award-winning software package developed by Professor Yang Zhang’s laboratory at the University of Michigan. Utilizing the I-TASSER protein structure prediction algorithms that combine threading and ab initio folding technologies, NovaFold works with Lasergene Protein to build accurate, full 3D atomic models of proteins with previously unknown structures.
NovaFold Antibody
NovaFold Antibody software is specifically designed to generate models of antibodies and antibody fragments (Fv, Fab, VH, sdAb). The NovaFold Antibody algorithm utilizes a combination of homology modeling and ab initio loop prediction, resulting in highly accurate predictions that are analyzed within Lasergene Protein.
NovaDock
NovaDock is a high-resolution protein-protein docking application that predicts atomic interactions between any two proteins. Simply provide your ligand and receptor sequence files, and NovaDock will predict the three-dimensional structure of the macromolecular complex for analysis in Lasergene Protein.
FAQs
How are Nova Applications sold?
A license of Lasergene Protein is required to run predictions with Nova Applications. NovaFold AI, NovaFold AI-Multimer, NovaFold, NovaFold Antibody, and NovaDock predictions can be purchased individually online. If you are interested in purchasing a bundle of predictions, please request a quote.
What are the technical requirements for running Nova Applications?
NovaFold, NovaFold Antibody and NovaDock can be run on the Cloud or locally on a server at your organization. NovaFold AI and NovaFold AI-Multimer are exclusively cloud-based. See our technical requirements for running Nova Applications locally. Lasergene Protein is required to run all Nova Applications.
Do you offer a free trial of Nova Applications?
One prediction for each of our Nova Applications is included in our Lasergene free trial. We also offer free, no-obligation, personalized demos of any of our Nova Applications with one of our scientists on staff, tailored to your specific research objectives.
