Hydropathy – Kyte-Doolittle

The Hydropathy – Kyte-Doolittle track predicts regional hydropathy of proteins from their amino acid sequences, using the approach of Kyte and Doolittle, 1982. Hydropathy values are assigned for all amino acids and are then averaged over a user-defined window. The average is plotted at the midpoint of the window. Residue hydropathy assignments are derived from water-vapor transfer free energies and the interior-exterior distribution of residue side-chains.

To apply this track to the sequence:

In the Tracks panel, expand Hydropathy and check the box next to Kyte-Doolittle. The track will now be visible in the Sequences view.

To edit track options:

Select the track in the Tracks panel. Open the Track Options section, which appears as follows:

• Residues to Average – the size of the window over which hydropathy values are averaged. It is recommended you select 7 to 11 residues. The default is 9.

Click if you wish to return to the default value.